The Greater Peterborough Innovation Cluster is a not-for-profit organization incorporated in 2004. As part of the Ontario Commercialization Network (OCN), the Innovation Cluster is one of twelve Regional Innovation Networks (RINs) in Ontario, Canada, ensuring that the programs and services of the Ontario Ministry of Research and Innovation are provided within the Peterborough Region.

The Innovation Cluster, previously known as the Greater Peterborough Region DNA Cluster, was established through Trent University, Sir Sandford Fleming College, Ontario Ministry Natural Resources, and the Greater Peterborough Area Economic Development Corporation (GPA EDC). In its inception it received funding from Trent University, Sir Sandford Fleming College, Industry Canada, Ministry of Economic Development and Trade, and the City of Peterborough.

Currently, the Innovation Cluster has expanded its scope to include innovation across multiple disciplines. It now receives its primary funding through the Ministry of Research and Innovation (MRI), Industry Canada, and its Private Sector Membership.